商品功能說明
Cefiderocol MTS™ (MIC Test Strip), FDC 0.016-256 μg/mL , is a quantitative method for the in-vitro susceptibility testing of Pseudomonas aeruginosa to Cefiderocol.
MTS™ consists of special porous paper impregnated with a pre-defined concentration gradient of an antimicrobial agent, used to determine the minimum inhibitory concentration (MIC) in μg/mL of antimicrobial agents against bacteria as tested on agar media using overnight incubation and manual reading procedures.
Cefiderocol is a siderophore cephalosporin with activity against aerobic Gram-negative organisms. It binds to free iron and is actively transported into bacterial cells through the outer membrane. This Trojan horse strategy allows cefiderocol to enter the space in-between the bacterial cell walls and disrupt cell wall synthesis. In addition, cefiderocol is stable against nearly all beta-lactamases, including both the serine and metallo-carbapenemases.
